Gender and Depression

How would you respond to this scenario?
 
For the past two weeks, Kate has been feeling really down. She wakes up in the morning with a flat, heavy feeling that sticks with her all day. She isn't enjoying things the way she normally would. In fact, nothing gives her pleasure. Even when good things happen, they don't seem to make Kate happy.
 
Would you say Kate was depressed?
 
Now, what would you think if in the same scenario, all the "she's" were "he's" and Kate was Jack?